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Santee, South Carolina Hotel Rooms & Luxury Resorts

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Holiday Inn Santee Santee, South Carolina Hotels & Resorts
From USD $
85
per Night

Holiday Inn Santee

Santee, South Carolina Hotels & Resorts

Holiday Inn Santee is located off Interstate 95, a mile from Santee Cooper Lake, and approximately 50 miles from Charleston International Airport.

Hampton Inn Santee Santee, South Carolina Hotels & Resorts
From USD $
77
per Night

Hampton Inn Santee

Santee, South Carolina Hotels & Resorts

The Hampton Inn Santee 50 miles from both the Charleston International airport and Columbia Metropolitan airport and is located within walking distance

Quality Inn And Suites Santee Santee, South Carolina Hotels & Resorts
From USD $
87
per Night

Quality Inn And Suites Santee

Santee, South Carolina Hotels & Resorts

Quality Inn And Sts Santee is located approximately 60 miles from the Columbia Airport, 60 miles from the Charleston International Airport, and 60 miles

Super 8 Santee Santee, South Carolina Hotels & Resorts
From USD $
47
per Night

Super 8 Santee

Santee, South Carolina Hotels & Resorts

With easy access off I-95 at exit 98, Super 8 Santee is approximately two minutes from three golf courses, half a mile from Santee Mall, and 40 miles from

Best Western Plus Santee Inn Santee, South Carolina Hotels & Resorts
From USD $
84
per Night

Best Western Plus Santee Inn

Santee, South Carolina Hotels & Resorts

Conveniently located off I-95, this Santee hotel offers cozy guest rooms and easy access to area attractions, including golf courses and state parks.

Howard Johnson Santee Santee, South Carolina Hotels & Resorts
From USD $
48
per Night

Howard Johnson Santee

Santee, South Carolina Hotels & Resorts

Located in the heart of South Carolina's premier golfing destinations, the Econo Lodge is ideally located walking distance from two of Santee's amazing

Travelodge SanteeSantee, South Carolina Hotels & Resorts
From USD $
55
per Night

Travelodge Santee

Santee, South Carolina Hotels & Resorts

Travelodge Santee is located approximately one mile from the downtown area and 55 miles from Charleston AFB International Airport.

Days Inn Summerton Summerton, South Carolina Hotels & Resorts
From USD $
40
per Night

Days Inn Summerton

Summerton, South Carolina Hotels & Resorts

With easy access off I-95 at Exit 108, the hotel is a short distance to Marions Lake fishing and boating amenities.

Days Inn Orangeburg South Orangeburg, South Carolina Hotels & Resorts
From USD $
50
per Night

Days Inn Orangeburg South

Orangeburg, South Carolina Hotels & Resorts

The Days Inn Orangeburg South offers budget-friendly accommodations approximately 40 miles from Columbia Metro Airport.

M Star Hotel Manning Manning, South Carolina Hotels & Resorts
From USD $
45
per Night

M Star Hotel Manning

Manning, South Carolina Hotels & Resorts

Get the best of the great outdoors and southern hospitality while visiting this Knights Inn hotel in Manning, SC.

Quality Inn Manning Manning, South Carolina Hotels & Resorts
From USD $
65
per Night

Quality Inn Manning

Manning, South Carolina Hotels & Resorts

The Quality Inn Manning hotel is conveniently located on Interstate 95, just 10 miles from Lake Marion, offering fishing, golfing, hunting and boating.

Super 8 Manning Manning, South Carolina Hotels & Resorts
From USD $
42
per Night

Super 8 Manning

Manning, South Carolina Hotels & Resorts

Super 8 Manning is located approximately 22 miles from Santee and 65 miles from Florence Regional Airport.

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Santee, South Carolina Hotel Rooms & Luxury Resorts

Find great deals on quality Santee, South Carolina hotels & resorts, or indulge at one of our luxury resorts. Take advantage of the many amenities that can be included with your stay such as in-room internet access, wifi, room service, fitness center, pool, hot tub, steam room, and shuttle services to and from the airport. Browse our Santee, South Carolina hotels and resorts and plan your Santee, South Carolina vacation today!


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