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Find great deals on quality Seneca, South Carolina hotels & resorts, or indulge at one of our luxury resorts. Take advantage of the many amenities that can be included with your stay such as in-room internet access, wifi, room service, fitness center, pool, hot tub, steam room, and shuttle services to and from the airport. Browse our Seneca, South Carolina hotels and resorts and plan your Seneca, South Carolina vacation today!


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Featured Listings

1 - 20 of 554 for Hotels & Resorts within 50 miles of Seneca, South Carolina
Tru by Hilton Columbia Greystone Hotels & Resorts Columbia, South Carolina

Tru by Hilton Columbia Greystone

Hotels & Resorts Columbia, South Carolina - 116.0 miles away
Our new Tru is three minutes from fun at Riverbanks Zoo and Gardens. Less than four miles from downtown Columbia, we are just off I-126. Enjoy free WiFi, a large HDTV with premium channels and our fre...
From USD $96 per night
Myrtle Beach SC Hotels, Resorts, and Condos Hotels & Resorts Myrtle Beach, South Carolina

Myrtle Beach SC Hotels, Resorts, and Condos

Hotels & Resorts Myrtle Beach, South Carolina - 117.5 miles away
Vacations Made Easy offers dozens of Myrtle Beach hotels, resorts, condos and vacation rentals from beach front to downtown. We also offer attractions such as the Dixie Stampede, Carolina Opry, and R...
From USD $65 per trip

Comfort Suites Anderson Hotels & Resorts Anderson, South Carolina

Comfort Suites Anderson

Hotels & Resorts Anderson, South Carolina - 15.8 miles away
This Comfort Suites is located approximately five miles from Pendleton's historic district and 40 miles from Greenville/Spartanburg Airport. ...
From USD $85 per night
Country Inn Suites Anderson Hotels & Resorts Anderson, South Carolina

Country Inn Suites Anderson

Hotels & Resorts Anderson, South Carolina - 15.7 miles away
Country Inn Suites Anderson is located 35 miles from Greenville/Spartanburg International Airport. ...
From USD $57 per night
Days Inn Anderson Hotels & Resorts Anderson, South Carolina

Days Inn Anderson

Hotels & Resorts Anderson, South Carolina - 15.7 miles away
The Days Inn Anderson/Clemson offers budget-friendly accommodations approximately eight miles from Anderson County Airport. ...
From USD $55 per night
Fairfield Inn And Suites By Marriott Anderson Clem Hotels & Resorts Anderson, South Carolina

Fairfield Inn And Suites By Marriott Anderson Clem

Hotels & Resorts Anderson, South Carolina - 15.7 miles away
Fairfield Inn and Suites by Marriott Anderson Clemson is accessible from Greenville-Spartanburg International Airport, and local attraction include Garrison ...
From USD $109 per night
Hampton Inn Anderson Hotels & Resorts Anderson, South Carolina

Hampton Inn Anderson

Hotels & Resorts Anderson, South Carolina - 16.8 miles away
The Hampton Inn® hotel in Anderson is located by Lake Hartwell near Clemson University, and with easy access to Belton, Honeapath, Pendleton, Williamston...
From USD $71 per night
Holiday Inn Express Anderson-i-85 Exit 27 At Hwy 8 Hotels & Resorts Anderson, South Carolina

Holiday Inn Express Anderson-i-85 Exit 27 At Hwy 8

Hotels & Resorts Anderson, South Carolina - 19.0 miles away
Off the I-85 at Exit 27 on Highway 81, Holiday Inn Express Anderson is 18 miles from downtown Greenville and approximately 35 miles from Greenville Spartanburg ...
From USD $68 per night
Holiday Inn Express And Suites Anderson Hotels & Resorts Anderson, South Carolina

Holiday Inn Express And Suites Anderson

Hotels & Resorts Anderson, South Carolina - 15.7 miles away
Located in the northwestern part of South Carolina, Holiday Inn Express and Suites Anderson is located approximately 40 miles from Greenville-Spartanburg ...
From USD $86 per night
Jameson Inn Anderson Hotels & Resorts Anderson, South Carolina

Jameson Inn Anderson

Hotels & Resorts Anderson, South Carolina - 16.8 miles away
You'll be well taken care of during your next trip to the Blue Ridge foothills when you book a room at the Baymont Inn and Suites Anderson/Clemson hotel. ...
From USD $75 per night
La Quinta Anderson Hotels & Resorts Anderson, South Carolina

La Quinta Anderson

Hotels & Resorts Anderson, South Carolina - 19.1 miles away
The La Quinta Anderson is southwest of Greenville, not far from the shores of Hartwell Lake and Clemson University and Stadium. ...
From USD $49 per night
Home Towne Suites Anderson Hotels & Resorts Anderson, South Carolina

Home Towne Suites Anderson

Hotels & Resorts Anderson, South Carolina - 18.6 miles away
Home-Towne Suites is located next to the civic center in Anderson, SC. ...
From USD $66 per night
Super 8 Anderson Clemson Area Hotels & Resorts Anderson, South Carolina

Super 8 Anderson Clemson Area

Hotels & Resorts Anderson, South Carolina - 18.8 miles away
The Super 8 Anderson Clemson Area is located approximately six miles northeast of the Anderson Airport. ...
From USD $45 per night

Americas Best Value Inn Anderson Hotels & Resorts Anderson, South Carolina

Americas Best Value Inn Anderson

Hotels & Resorts Anderson, South Carolina - 17.8 miles away
Welcome to the Americas Best Value Inn of Anderson, South Carolina. We are conveniently located just 1 1/2 miles south of I-85 at exit 19A along US Hwy ...
From USD $45 per night
Hilton Garden Inn Anderson Hotels & Resorts Anderson, South Carolina

Hilton Garden Inn Anderson

Hotels & Resorts Anderson, South Carolina - 16.4 miles away
The Hilton Garden Inn Anderson is in the beautiful upstate area of South Carolina, conveniently located off Interstate 85 at Exit 19A. ...
From USD $81 per night
Holiday Inn Anderson Hotels & Resorts Anderson, South Carolina

Holiday Inn Anderson

Hotels & Resorts Anderson, South Carolina - 18.7 miles away
We invite you to experience the brand new Holiday Inn Anderson Clemson area the newest full service Anderson hotel. Easily accessed from I 85 at exit 21 ...
From USD $75 per night
Microtel Inn Anderson Clemson Hotels & Resorts Anderson, South Carolina

Microtel Inn Anderson Clemson

Hotels & Resorts Anderson, South Carolina - 15.8 miles away
Nearby attractions include Anderson Civic Center and Great Southeast Balloon two miles away, Anderson University and Ed Garrison Livestock five miles away...
From USD $70 per night
Quality Inn Anderson Hotels & Resorts Anderson, South Carolina

Quality Inn Anderson

Hotels & Resorts Anderson, South Carolina - 19.7 miles away
The Quality Inn is located in Anderson, one mile from the Anderson Civic Center, three miles from Lake Hartwell, and eight miles from Garrison Arena. ...
From USD $50 per night
Hampton Inn Anderson Alliance Business Park Hotels & Resorts Anderson, South Carolina

Hampton Inn Anderson Alliance Business Park

Hotels & Resorts Anderson, South Carolina - 19.2 miles away
The Hampton Inn® Anderson/Alliance Business Park hotel is located minutes from downtown Anderson, as well as Clemson and Anderson universities. ...
From USD $84 per night
Comfort Inn Clemson Hotels & Resorts Clemson, South Carolina

Comfort Inn Clemson

Hotels & Resorts Clemson, South Carolina - 5.8 miles away
The Comfort Inn offers affordable accommodations in Clemson, SC, approximately two miles from Oconee Airport and about 45 miles from Greenville/Spartanburg ...
From USD $90 per night


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