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Find great deals on quality Sikeston, Missouri hotels & resorts, or indulge at one of our luxury resorts. Take advantage of the many amenities that can be included with your stay such as in-room internet access, wifi, room service, fitness center, pool, hot tub, steam room, and shuttle services to and from the airport. Browse our Sikeston, Missouri hotels and resorts and plan your Sikeston, Missouri vacation today!


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Featured Listings

1 - 20 of 349 for Hotels & Resorts within 50 miles of Sikeston, Missouri
Seven Gables Inn St. Louis Hotels & Resorts St. Louis, Missouri

Seven Gables Inn St. Louis

Hotels & Resorts St. Louis, Missouri - 128.2 miles away
The Seven Gables Inn is a boutique hotel in Saint Louis that provides delightful accommodations with the intimacy of a bed and breakfast. Located just fifteen minutes from Lambert Airport and ten minu...
From USD $99 per night

Drury Lodge Cape Girardeau Hotels & Resorts Cape Girardeau, Missouri

Drury Lodge Cape Girardeau

Hotels & Resorts Cape Girardeau, Missouri - 28.1 miles away
Now serving FREE HOT QUIKSTART Breakfast. Enjoy scrambled eggs, sausage,Belgian waffles, biscuits and gravy and much more. Also, FREE high-speed internet ...
From USD $80 per night
Drury Suites Cape Girardeau Hotels & Resorts Cape Girardeau, Missouri

Drury Suites Cape Girardeau

Hotels & Resorts Cape Girardeau, Missouri - 27.9 miles away
The Drury Suites Cape Girardeau is six miles from the Cape Girardeau Regional airport and is three miles from the Downtown/ Riverfront, Shawnee Park Sports ...
From USD $106 per night
Pear Tree Inn Cape Girardeau Hotels & Resorts Cape Girardeau, Missouri

Pear Tree Inn Cape Girardeau

Hotels & Resorts Cape Girardeau, Missouri - 28.0 miles away
The Pear Tree Inn Cape Girardeau is located at a major I-55 exit and within blocks of shopping, health care facilities, and Southwest Missouri State University. ...
From USD $67 per night
Victorian Inn And Suites Hotels & Resorts Cape Girardeau, Missouri

Victorian Inn And Suites

Hotels & Resorts Cape Girardeau, Missouri - 27.8 miles away
Free breakfast with over 25 items, indoor heated pool, large whirlpool, deli and bar, free high speed wireless internet in every room, recently renovated...
From USD $74 per night
Hampton Inn Cape Giradeau Hotels & Resorts Cape Girardeau, Missouri

Hampton Inn Cape Giradeau

Hotels & Resorts Cape Girardeau, Missouri - 27.9 miles away
The Hampton Inn Cape Girardeau hotel is located off Interstate 55 and four miles west of downtown Cape Girardeau, Missouri. Area attractions near our hotel ...
From USD $99 per night
Holiday Inn Express Suites Cape Girardeau Hotels & Resorts Cape Girardeau, Missouri

Holiday Inn Express Suites Cape Girardeau

Hotels & Resorts Cape Girardeau, Missouri - 27.9 miles away
Holiday Inn Express & Suites Cape Girardeau is located approximately two miles from the Mississippi River Wall of Fame Murals and six miles from Cape Girardeau ...
From USD $99 per night
Super 8 Cape Girardeau Mo Hotels & Resorts Cape Girardeau, Missouri

Super 8 Cape Girardeau Mo

Hotels & Resorts Cape Girardeau, Missouri - 30.8 miles away
The Super 8 Cape Girardeau is approximately seven miles from Cape Girardeau Airport. ...
From USD $59 per night
Candlewood Suites Cape Girarde Hotels & Resorts Cape Girardeau, Missouri

Candlewood Suites Cape Girarde

Hotels & Resorts Cape Girardeau, Missouri - 27.1 miles away
The Candlewood Suites Cape Girardeau Hotel is conveniently located off Interstate 55 at exit 95. Nearby places of attractions includes Southeast Missouri ...
From USD $85 per night
Econo Lodge Charleston Hotels & Resorts Charleston, Missouri

Econo Lodge Charleston

Hotels & Resorts Charleston, Missouri - 13.4 miles away
Depend on the Super 8 Charleston hotel to honor the Super 8 8-Point Promise in this Missouri destination. ...
From USD $60 per night
Oak Tree Inn Dexter Hotels & Resorts Dexter, Missouri

Oak Tree Inn Dexter

Hotels & Resorts Dexter, Missouri - 24.0 miles away
With extra-quiet guest rooms and light-proof draperies, the Oak Tree Inn Dexter is Dexters newest hotel. ...
From USD $69 per night
Hickory House Inn Hotels & Resorts Dexter, Missouri

Hickory House Inn

Hotels & Resorts Dexter, Missouri - 23.6 miles away
The Hickory House Inn is situated 25 miles from the Mingo National Wildlife and 2.5 miles from the Heritage House. Ground floor rooms, and at-the-door ...
From USD $50 per night

Drury Inn And Suites Hayti Hotels & Resorts Hayti, Missouri

Drury Inn And Suites Hayti

Hotels & Resorts Hayti, Missouri - 46.9 miles away
The Drury Inn Suites Hayti Crthsvl is located near Interstates 55 and 155. Nearby attarctions includes Caruthersville Airport, Caruthersville Health Center...
From USD $80 per night
Comfort Inn Hayti Hotels & Resorts Hayti, Missouri

Comfort Inn Hayti

Hotels & Resorts Hayti, Missouri - 47.0 miles away
The Comfort Inn in Hayti is conveniently located off Interstate 55, between St. Louis and Memphis. ...
From USD $75 per night
Drury Inn And Suites Jackson Hotels & Resorts Jackson, Missouri

Drury Inn And Suites Jackson

Hotels & Resorts Jackson, Missouri - 36.7 miles away
The Drury Inn and Suites Jackson MO is located 15 miles from Cape Girardeau Regional Airport and eight miles from Rocky Holler Usa. ...
From USD $80 per night
Comfort Suites Jackson Hotels & Resorts Jackson, Missouri

Comfort Suites Jackson

Hotels & Resorts Jackson, Missouri - 31.6 miles away
The Comfort Suites Jackson is convenient location off Interstate 55 and Highway 61. Convenient to Southeast Missouri State University, Show Me Center and ...
From USD $71 per night
Super 8 Marston New Madrid Hotels & Resorts Marston, Missouri

Super 8 Marston New Madrid

Hotels & Resorts Marston, Missouri - 26.3 miles away
This Super 8 is located off of I-55, Exit 40, and is approximately 53 miles from Cape Girardeau Municipal Airport. ...
From USD $48 per night
Comfort Inn Poplar Bluff Hotels & Resorts Poplar Bluff, Missouri

Comfort Inn Poplar Bluff

Hotels & Resorts Poplar Bluff, Missouri - 48.3 miles away
Located near hospital and community college. Walking distance to shopping and restaurants. 3 miles to Popular Bluff Industrial Park. ...
From USD $95 per night
Drury Inn Poplar Bluff Hotels & Resorts Poplar Bluff, Missouri

Drury Inn Poplar Bluff

Hotels & Resorts Poplar Bluff, Missouri - 48.0 miles away
Now serving FREE HOT QUIKSTART Breakfast. Enjoy scrambled eggs, sausage, Belgian waffles, biscuits and gravy and much more. Also, new for 2003 FREE high-speed ...
From USD $96 per night


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